Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 17/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16485801 | 1.00 | CTSC (0.46) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16485795 | 0.90 | CTSC (0.47) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16485754 | 0.90 | CTSC (0.44) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16485791 | 0.89 | CTSC (0.44) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16485823 | 0.89 | CTSC (0.42) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16485830 | 0.88 | CTSC (0.41) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16485781 | 0.88 | CTSC (0.43) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16478076 | 0.88 | CTSC (0.50) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16478155 | 0.88 | CTSC (0.50) | CTSCKCNH2CTSKCTSSLTB4R | |
| SCHEMBL16485755 | 0.86 | CTSC (0.42) | CTSCKCNH2CTSKCTSSLTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |