Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 12/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | APC | P25054 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2893127 | 0.91 | ECE1 (0.38) | ECE1ITGA4ITGB7RETREN | |
| SCHEMBL2893129 | 0.91 | ECE1 (0.38) | ECE1ITGA4ITGB7RETREN | |
| SCHEMBL16478298 | 0.90 | ECE1 (0.43) | ECE1ITGA4 | |
| SCHEMBL16485829 | 0.88 | CTSC (0.40) | RETCTSK | |
| SCHEMBL16485757 | 0.85 | ECE1 (0.40) | ECE1ITGA4ITGB7RETREN | |
| SCHEMBL9886055 | 0.84 | CTSC (0.41) | ECE1ITGA4ITGB7RETREN | |
| SCHEMBL16478325 | 0.81 | ECE1 (0.42) | ECE1ITGA4ITGB7CTSK | |
| SCHEMBL16485763 | 0.80 | ECE1 (0.41) | ECE1ITGA4ITGB7RENAPC | |
| SCHEMBL16485782 | 0.79 | CTSC (0.48) | RETCTSSCTSK | |
| SCHEMBL16485771 | 0.79 | CTSC (0.38) | ECE1ITGA4ITGB7RENAPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |