Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.86 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.64 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16790694 | 0.93 | TP53 (1.00) | TP53POLBMEN1KMT2AMAPT | |
| SCHEMBL11919993 | 0.91 | KMT2A (0.77) | TP53POLBMEN1GAAKMT2A | |
| SCHEMBL16486900 | 0.91 | SMN1; SMN2 (0.74) | TP53POLBMEN1GAAKMT2A | |
| SCHEMBL16486486 | 0.84 | TP53 (0.72) | TP53POLBMEN1KMT2AMAPT | |
| SCHEMBL15606897 | 0.83 | TP53 (0.83) | TP53POLBMEN1GAAKMT2A | |
| SCHEMBL15606898 | 0.83 | TP53 (0.83) | TP53POLBMEN1KMT2AMAPT | |
| SCHEMBL16486439 | 0.83 | POLB (0.80) | TP53POLBMEN1KMT2AMAPT | |
| SCHEMBL15606900 | 0.78 | POLB (1.00) | TP53POLBMEN1GAAKMT2A | |
| SCHEMBL13831342 | 0.78 | MAPT (0.75) | TP53POLBMAPTPTK2TSHR | |
| SCHEMBL15986410 | 0.77 | POLB (0.78) | TP53POLBMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015021943-A9 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015021943-A1 | INDUCING NEUROGENESIS BY AXIN ENHANCER | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-02-19 | — | — | WO | disclosed |