SCHEMBL1648797

SCHEMBL1648797

C1=C\C=C/c2ncccc2\C=C/1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
S100A4 P26447 1/20 0.34
CDC25B P30305 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
BLM P54132 2/20 0.33
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33
ABL1 P00519 1/20 0.33
PLCG1 P19174 1/20 0.33
CES1 P23141 1/20 0.33
PAX8 Q06710 1/20 0.33
RIN1 Q13671 1/20 0.33
THRB P10828 1/20 0.33
GAA P10253 1/20 0.33
KDM4E B2RXH2 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1648800 1.00 CA12 (0.42) CA12CA1CA2CA9S100A4
SCHEMBL27847095 0.98 CA12 (0.41) CA12CA1CA2CA9S100A4
Iodide SCHEMBL3908349 0.98 CA12 (0.41) CA12CA1CA2CA9S100A4
Iodide SCHEMBL3908355 0.98 CA12 (0.41) CA12CA1CA2CA9S100A4
SCHEMBL3261185 0.82
SCHEMBL4866082 0.81
SCHEMBL21319387 0.75 CDC25B (0.41) CA12CA1CA2CA9S100A4
SCHEMBL7056579 0.75 CDC25B (0.41) CA12CA1CA2CA9S100A4
SCHEMBL7056574 0.75 CDC25B (0.41) CA12CA1CA2CA9S100A4
SCHEMBL23330240 0.73 CA12 (0.44) CA12CA1CA2CA9S100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1792605-A1 Use of at least a cationic cyanine derivative for use in hair dyeing, composition containg it process of treating keratinic fibres using the same composition, kit and use thereof L'Oréal (FR) 2007-06-06 EP claimed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed
EP-1792605-A1 Use of at least a cationic cyanine derivative for use in hair dyeing, composition containg it process of treating keratinic fibres using the same composition, kit and use thereof L'Oréal (FR) 2007-06-06 EP disclosed