SCHEMBL16488191

SCHEMBL16488191

O=C(OC1CC1)C1OC1I

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14967741 0.77 PPM1B (0.32) SERPINE1
SCHEMBL11188748 0.74 EPHX1 (0.42)
SCHEMBL11193873 0.74 CYP19A1 (0.39)
SCHEMBL29353235 0.73 EPHX1 (0.45)
SCHEMBL11190659 0.73 EPHX1 (0.45)
SCHEMBL11194073 0.73 EPHX1 (0.45)
SCHEMBL14967440 0.71 PPM1B (0.35)
SCHEMBL14967204 0.70 EPHX1 (0.36)
SCHEMBL14966833 0.70 EPHX1 (0.40)
SCHEMBL828099 0.69 FABP7 (0.40) SERPINE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2837629-B1 METHOD FOR SYNTHESIZING SAPROPTERIN DIHYDROCHLORIDE ASYMCHEM LABORATORIES (TIANJIN) CO LTD (CN) 2017-03-22 EP disclosed
EP-2837629-A1 METHOD FOR SYNTHESIZING SAPROPTERIN DIHYDROCHLORIDE Asymchem Laboratories (Tianjin) Co., Ltd (CN) 2015-02-18 EP disclosed