Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 14/20 | 0.78 |
| ▸ | ATM | Q13315 | 5/20 | 0.54 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256572 | 0.87 | PRKDC (1.00) | PRKDCATM | |
| SCHEMBL16215855 | 0.80 | PRKDC (0.65) | PRKDC | |
| SCHEMBL256584 | 0.79 | PRKDC (0.64) | PRKDCATM | |
| SCHEMBL10059173 | 0.79 | PRKDC (0.82) | PRKDCATM | |
| SCHEMBL20031059 | 0.78 | PRKDC (0.77) | PRKDCATM | |
| SCHEMBL257162 | 0.78 | PRKDC (0.78) | PRKDCATM | |
| SCHEMBL10060791 | 0.77 | PRKDC (1.00) | PRKDCATM | |
| SCHEMBL167830 | 0.76 | PRKDC (0.75) | PRKDCATM | |
| SCHEMBL256573 | 0.76 | PRKDC (0.74) | PRKDCATM | |
| SCHEMBL167275 | 0.76 | PRKDC (1.00) | PRKDCATMGPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609082-B1 | IMIDAZO[4,5-C]QUINOLINES AS DNA-PK INHIBITORS | MERCK PATENT GMBH (DE) | 2015-02-18 | — | — | EP | disclosed |