Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 16/20 | 0.63 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257582 | 0.96 | PRKDC (0.66) | PRKDCATMCSF1R | |
| SCHEMBL257162 | 0.89 | PRKDC (0.78) | PRKDCATMCSF1R | |
| SCHEMBL256574 | 0.83 | PRKDC (0.70) | PRKDCATM | |
| SCHEMBL257311 | 0.79 | PRKDC (0.60) | PRKDCATM | |
| SCHEMBL10059983 | 0.78 | PRKDC (0.57) | PRKDCATM | |
| SCHEMBL256572 | 0.77 | PRKDC (1.00) | PRKDCATM | |
| SCHEMBL10060791 | 0.77 | PRKDC (1.00) | PRKDCATM | |
| SCHEMBL15064494 | 0.76 | PRKDC (0.59) | PRKDCATM | |
| SCHEMBL15006872 | 0.76 | PRKDC (0.72) | PRKDC | |
| SCHEMBL15006756 | 0.74 | PRKDC (0.86) | PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609082-B1 | IMIDAZO[4,5-C]QUINOLINES AS DNA-PK INHIBITORS | MERCK PATENT GMBH (DE) | 2015-02-18 | — | — | EP | disclosed |