Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654263 | 0.88 | APP (0.41) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3659775 | 0.83 | APP (0.63) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3656710 | 0.81 | APP (0.37) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3655774 | 0.81 | APP (0.37) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3656021 | 0.77 | APP (0.47) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL13968116 | 0.73 | APP (0.42) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3661808 | 0.72 | CNR2 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL3657568 | 0.72 | APP (0.50) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3657899 | 0.72 | APP (0.49) | APPPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1201874 | 0.72 | GAA (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234954-B1 | TETRASUBSTITUTED BENZENES | ENVIVO PHARMACEUTICALS INC (US) | 2015-02-18 | — | — | EP | disclosed |