SCHEMBL16488489

SCHEMBL16488489

C/C=C/CCC1CCC(C2CCC(c3ccc(-c4cc(F)c(F)c(F)c4)c(F)c3)CC2)CC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
FASN P49327 1/20 0.30
APP P05067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12626307 0.89
SCHEMBL13614882 0.89 CYP3A4 (0.33) CYP3A4CYP2C9FASNAPP
SCHEMBL8451027 0.87
SCHEMBL13615016 0.87 CYP3A4 (0.34) CYP3A4CYP2C9FASNAPP
SCHEMBL8959378 0.86 CYP3A4 (0.34) CYP3A4CYP2C9FASNAPP
SCHEMBL16488488 0.86 CYP3A4 (0.31) CYP3A4CYP2C9
SCHEMBL16521128 0.85
SCHEMBL12625198 0.85
SCHEMBL1754930 0.85 CYP2C9 (0.41) CYP3A4CYP2C9FASNAPP
SCHEMBL18472161 0.85 CYP2C9 (0.41) CYP3A4CYP2C9FASNAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2837670-B1 FLUOROBIPHENYL-CONTAINING COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2017-09-27 EP disclosed
US-9441160-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2016-09-13 US disclosed
US-9441160-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2016-09-13 US disclosed
US-9181478-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2015-11-10 US disclosed
US-9181478-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2015-11-10 US disclosed
US-20150291881-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-10-15 US disclosed
US-20150291881-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-10-15 US disclosed
US-20150252263-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-09-10 US disclosed
US-20150252263-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-09-10 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
EP-2837670-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC Corporation (JP) 2015-02-18 EP disclosed