Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.59 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.50 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661152 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL31510307 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL31510305 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24637661 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL10191035 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL23077610 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL12937922 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19543682 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15315671 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL31225700 | 0.90 | F2 (0.60) | PKMPRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9645140-B2 | Labeling and detection of post translationally modified proteins | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-9645140-B2 | Labeling and detection of post translationally modified proteins | Life Technologies Corporation (US) | 2017-05-09 | — | — | US | disclosed |
| US-20150051096-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | Life Technologies Corporation | 2015-02-19 | — | — | US | disclosed |
| US-20150051096-A1 | LABELING AND DETECTION OF POST TRANSLATIONALLY MODIFIED PROTEINS | Life Technologies Corporation | 2015-02-19 | — | — | US | disclosed |