Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 8/20 | 0.47 |
| ▸ | CTSB | P07858 | 3/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 5/20 | 0.40 |
| ▸ | PLAT | P00750 | 2/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 5/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14685066 | 1.00 | CAPN1 (0.47) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL14672865 | 0.84 | CAPN1 (0.64) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL20958599 | 0.84 | CAPN1 (0.64) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL14728349 | 0.84 | CAPN1 (0.57) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL14672864 | 0.84 | CAPN1 (0.64) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL14682322 | 0.84 | CAPN1 (0.64) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL24171144 | 0.81 | CAPN1 (0.51) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL13964352 | 0.81 | CAPN1 (0.51) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL18539497 | 0.81 | CAPN1 (0.51) | CAPN1CTSBDPP4PREPDPP7 | |
| SCHEMBL16448429 | 0.81 | CAPN1 (0.51) | CAPN1CTSBDPP4PREPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160368947-A1 | NMDA Receptor Modulators and Uses Thereof | INNOVIVA TRC HOLDINGS LLC | 2016-12-22 | — | — | US | disclosed |
| US-20150315237-A1 | NMDA Receptor Modulators and Uses Thereof | NORTHWESTERN UNIVERSITY | 2015-11-05 | — | — | US | disclosed |
| US-20150051262-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051262-A1 | NMDA RECEPTOR MODULATORS AND USES THEREOF | GRIN1, GRIN2A, GRIN3A | CAPN1 866/4885CTSB 4049/4885DPP4 1407/4885 |
| US-20150315237-A1 | NMDA Receptor Modulators and Uses Thereof | GRIN1, GRIN2A, GRIN3A | CAPN1 866/4885CTSB 4049/4885DPP4 1407/4885 |
| US-20160368947-A1 | NMDA Receptor Modulators and Uses Thereof | GRIN1, GRIN2A, GRIN3A | CAPN1 866/4885CTSB 4049/4885DPP4 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.