SCHEMBL1648988

SCHEMBL1648988

CC(Cc1ccc(O)cc1)c1cccc(C(C)Cc2ccc(O)cc2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 8/20 0.71
ESR2 Q92731 8/20 0.71
TAAR1 Q96RJ0 3/20 0.57
SLC6A2 P23975 2/20 0.57
ADRB2 P07550 6/20 0.44
CYP3A4 P08684 3/20 0.44
MAPK1 P28482 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
CYP2D6 P10635 1/20 0.44
TSHR P16473 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ADRB1 P08588 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
ADRB3 P13945 1/20 0.44
PTGS1 P23219 1/20 0.44
HTR2A P28223 1/20 0.44
SLC6A4 P31645 1/20 0.44
MC4R P32245 1/20 0.44
ADRA1A P35348 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10456437 0.93 ESR1 (0.67) ESR1ESR2TAAR1SLC6A2ADRB2
SCHEMBL27958166 0.90 ESR1 (0.80) ESR1ESR2TAAR1SLC6A2ADRB2
SCHEMBL25380112 0.90 ESR1 (0.73) ESR1ESR2TAAR1SLC6A2CYP3A4
SCHEMBL27981745 0.88 ESR1 (0.61) ESR1ESR2TAAR1SLC6A2ADRB2
SCHEMBL900979 0.88 ESR1 (0.61) ESR1ESR2TAAR1SLC6A2ADRB2
SCHEMBL4602654 0.86 ESR1 (0.81) ESR1ESR2TAAR1SLC6A2OPRM1
SCHEMBL1936402 0.86 ESR1 (0.81) ESR1ESR2TAAR1SLC6A2OPRM1
Ammonia Solution, Strong SCHEMBL8866157 0.85 ESR1 (0.78) ESR1ESR2TAAR1SLC6A2OPRM1
SCHEMBL25382615 0.84 ESR1 (0.56) ESR1ESR2TAAR1SLC6A2HDAC4
SCHEMBL296781 0.84 ESR1 (1.00) ESR1ESR2TAAR1SLC6A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115698110-B Resin composition for curing, molded article, and method for producing same 三菱瓦斯化学株式会社 2025-04-29 CN disclosed
CN-119053452-A Thermosensitive recording medium 王子控股株式会社 2024-11-29 CN disclosed
CN-118973826-A Thermosensitive recording medium 王子控股株式会社 2024-11-15 CN disclosed
CN-117957123-A Thermosensitive recording medium 王子控股株式会社 2024-04-30 CN disclosed
CN-116490375-A Thermosensitive recording medium 王子控股株式会社 2023-07-25 CN disclosed
EP-2552995-B2 MELT POLYCARBONATE HAVING IMPROVED HEAT AGEING COVESTRO DEUTSCHLAND AG (DE) 2022-01-05 EP disclosed
CN-113348006-A Crack-resistant member 株式会社大赛璐 2021-09-03 CN disclosed
US-20170340955-A1 THERMALLY IMAGEABLE SUBSTRATE WITH ENCAPSULATED COREACTANT APPVION OPERATIONS, INC. 2017-11-30 US disclosed
US-20160096105-A1 Direct Thermal Variable Printing Substrate APPVION, INC. (US) 2016-04-07 US disclosed
EP-2552995-B1 MELT POLYCARBONATE HAVING IMPROVED HEAT AGEING COVESTRO DEUTSCHLAND AG (DE) 2015-12-02 EP disclosed
EP-1377625-A1 POLYCARBONATE HAVING A PRONOUNCED SHEAR THINNING BEHAVIOR Bayer Aktiengesellschaft (DE) 2004-01-07 EP disclosed
EP-1377624-A1 POLYCARBONATE HAVING A LOW SHEAR THINNING RATIO Bayer Aktiengesellschaft (DE) 2004-01-07 EP disclosed
US-20030027973-A1 Polycarbonate having a low shear thinning behavior BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
US-20030013839-A1 Polycarbonate having pronounced shear thinning behavior BAYER AKTIENGESELLSCHAFT (DE) 2003-01-16 US disclosed
US-20030013788-A1 Melt polycarbonate with improved resistance to hydrolysis BAYER AKTIENGESELLSCHAF (DE) 2003-01-16 US disclosed
WO-2002077064-A1 POLYCARBONATE HAVING A LOW SHEAR THINNING RATIO BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
WO-2002077101-A2 MELT POLYCARBONATE EXHIBITING AN IMPROVED RESISTANCE TO HYDROLYSIS BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
WO-2002077065-A1 POLYCARBONATE HAVING A PRONOUNCED SHEAR THINNING BEHAVIOR BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US disclosed