Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 11/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | CDK4 | P11802 | 2/20 | 0.48 |
| ▸ | CCND1 | P24385 | 2/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.44 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14851898 | 0.87 | PI4KB (0.61) | NPC1RAB9API4KBACHEADORA1 | |
| SCHEMBL16490541 | 0.80 | PI4KB (0.69) | PI4KB | |
| SCHEMBL16490517 | 0.80 | PI4KB (0.69) | PI4KB | |
| SCHEMBL14851841 | 0.77 | PI4KB (0.87) | PI4KB | |
| SCHEMBL14851710 | 0.77 | PI4KB (0.87) | PI4KB | |
| SCHEMBL17904362 | 0.76 | PI4KB (0.78) | PI4KB | |
| SCHEMBL17904357 | 0.76 | PI4KB (0.78) | PI4KB | |
| SCHEMBL17904363 | 0.76 | PI4KB (0.77) | PI4KB | |
| SCHEMBL16490576 | 0.75 | PI4KB (0.71) | PI4KB | |
| SCHEMBL18480756 | 0.74 | CDK4 (0.51) | NPC1RAB9API4KBCDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309236-B2 | PI-kinase inhibitors with broad spectrum anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150051193-A1 | PI-kinase Inhibitors with Broad Spectrum Anti-Infective Activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051193-A1 | PI-kinase Inhibitors with Broad Spectrum Anti-Infective Activity | PIP4K2A, PIP5K1A, PIP4K2C | NPC1 4136/4885RAB9A 1890/4885PI4KB 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.