Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 16/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 15/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.61 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.61 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.61 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.61 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.61 |
| ▸ | PI4KA | P42356 | 1/20 | 0.61 |
| ▸ | PRKDC | P78527 | 1/20 | 0.61 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14851755 | 0.92 | PIK3CG (0.75) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL16492668 | 0.90 | PIK3CD (0.75) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL16490588 | 0.86 | PIK3CD (0.62) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL16490591 | 0.84 | PIK3CD (0.59) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL16490380 | 0.80 | PIK3CD (0.62) | PIK3CGPIK3CDPIK3CAPIK3C3PI4KB | |
| SCHEMBL14851735 | 0.77 | PIK3CD (0.77) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL14851608 | 0.77 | PIK3CD (0.77) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL48649 | 0.76 | PIK3CD (1.00) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL29373332 | 0.76 | PIK3CD (1.00) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 | |
| SCHEMBL16490590 | 0.76 | PIK3CG (0.59) | PIK3CGPIK3CDPIK3CAPIK3CBPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309236-B2 | PI-kinase inhibitors with broad spectrum anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150051193-A1 | PI-kinase Inhibitors with Broad Spectrum Anti-Infective Activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051193-A1 | PI-kinase Inhibitors with Broad Spectrum Anti-Infective Activity | PIP4K2A, PIP5K1A, PIP4K2C | PIK3CG 22/4885PIK3CD 20/4885PIK3CA 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.