Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 9/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3655122 | 1.00 | OPRL1 (0.50) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL16494163 | 1.00 | OPRL1 (0.50) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL16494165 | 1.00 | OPRL1 (0.50) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL16493957 | 1.00 | OPRL1 (0.50) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL3648812 | 0.93 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL3650548 | 0.93 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL651020 | 0.88 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL648201 | 0.88 | OPRL1 (0.48) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL10092903 | 0.87 | OPRL1 (0.47) | OPRL1OPRM1OPRK1OPRD1CCR5 | |
| SCHEMBL650691 | 0.87 | OPRL1 (0.47) | OPRL1OPRM1OPRK1OPRD1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197843-B1 | PIPERIDINE DERIVATIVES AS AGONISTS OF MUSCARINIC RECEPTORS | ASTRAZENECA AB (SE) | 2011-12-28 | — | — | EP | claimed |