Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277869 | 0.85 | KMT2A (0.46) | KMT2AMEN1TSHRCA12CA14 | |
| SCHEMBL22216388 | 0.81 | GAA (0.48) | KMT2AMEN1TSHRGAAMGAM | |
| SCHEMBL16495375 | 0.81 | MEN1 (0.42) | KMT2AMEN1TSHRCA12CA14 | |
| SCHEMBL20126039 | 0.77 | KMT2A (0.44) | KMT2AMEN1TSHRCA12CA14 | |
| SCHEMBL8395382 | 0.75 | KMT2A (0.56) | KMT2AMEN1TSHRCA12CA14 | |
| SCHEMBL17232315 | 0.75 | KMT2A (0.56) | KMT2AMEN1TSHRCA12CA14 | |
| SCHEMBL5595576 | 0.74 | KMT2A (0.59) | KMT2AMEN1TSHRCA12CA14 | |
| SCHEMBL16494983 | 0.74 | KMT2A (0.59) | KMT2AMEN1TSHRCA12CA14 | |
| SCHEMBL18724616 | 0.73 | EPHX2 (0.51) | TSHRCA12CA14CA7CA9 | |
| Hydrochloric Acid SCHEMBL5595816 | 0.72 | KMT2A (0.63) | KMT2AMEN1TSHRCA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526945-A1 | New CRTH2 Antagonists | Almirall, S.A. (ES) | 2012-11-28 | — | — | EP | disclosed |
| EP-2526945-A1 | New CRTH2 Antagonists | Almirall, S.A. (ES) | 2012-11-28 | — | — | EP | disclosed |