Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 15/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.35 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21586639 | 0.84 | TYMP (0.66) | TYMPADORA1 | |
| SCHEMBL17968545 | 0.80 | TYMP (0.61) | TYMPADORA1 | |
| SCHEMBL17729103 | 0.77 | TYMP (0.49) | TYMP | |
| SCHEMBL17766490 | 0.77 | TYMP (0.49) | TYMP | |
| SCHEMBL3068469 | 0.76 | TYMP (0.42) | TYMP | |
| SCHEMBL5710025 | 0.76 | TYMP (0.62) | TYMP | |
| SCHEMBL23778466 | 0.76 | TYMP (0.54) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL29053753 | 0.76 | TYMP (0.54) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL29053752 | 0.76 | TYMP (0.54) | TYMPSLC6A1SLC6A11 | |
| SCHEMBL22577537 | 0.76 | TYMP (0.60) | TYMPADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110300142-A1 | USE OF ZEBURALINE FOR THE TREATMENT OF AUTOIMMUNE DISEASES OR IMMUNE REJECTION OF TRANSPLANTS | IDOGEN AB (SE) | 2011-12-08 | — | — | US | disclosed |