Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 14/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1488671 | 0.92 | S1PR1 (0.43) | S1PR1KDM4EHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL1647935 | 0.92 | S1PR1 (0.54) | S1PR1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1489001 | 0.91 | S1PR1 (0.51) | S1PR1KDM4EHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL1489274 | 0.88 | S1PR1 (0.56) | S1PR1KDM4EHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL1489310 | 0.85 | S1PR1 (0.53) | S1PR1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL12780065 | 0.85 | S1PR1 (0.46) | S1PR1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1489933 | 0.84 | S1PR1 (0.56) | S1PR1HSD17B10ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL1489212 | 0.83 | S1PR1 (0.51) | S1PR1KDM4EHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL1488870 | 0.83 | S1PR1 (0.63) | S1PR1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1489469 | 0.82 | S1PR1 (0.50) | S1PR1KDM4EHSD17B10ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2305660-A1 | New thiadiazole derivatives | Almirall, S.A. (ES) | 2011-04-06 | — | — | EP | disclosed |
| EP-2305660-A1 | New thiadiazole derivatives | Almirall, S.A. (ES) | 2011-04-06 | — | — | EP | disclosed |