Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 13/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16497483 | 1.00 | P2RY6 (0.37) | P2RY6P2RY2P2RY4 | |
| SCHEMBL16712345 | 0.86 | P2RY6 (0.42) | P2RY6P2RY2P2RY4 | |
| SCHEMBL16712346 | 0.86 | P2RY6 (0.42) | P2RY6P2RY2P2RY4 | |
| SCHEMBL16496845 | 0.85 | P2RY6 (0.42) | P2RY6P2RY2P2RY4 | |
| SCHEMBL16496846 | 0.85 | P2RY6 (0.42) | P2RY6P2RY2P2RY4 | |
| SCHEMBL16497534 | 0.85 | P2RY6 (0.42) | P2RY6P2RY2P2RY4 | |
| SCHEMBL16497307 | 0.83 | TYMP (0.37) | — | |
| SCHEMBL16497308 | 0.83 | TYMP (0.37) | — | |
| SCHEMBL16497241 | 0.81 | ST6GAL1 (0.34) | — | |
| SCHEMBL16497242 | 0.81 | ST6GAL1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720890-B1 | PHOSPONATE NUCLEOSIDES USEFUL AS ACTIVE INGREDIENTS IN PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS, AND INTERMEDIATES FOR THEIR PRODUCTION | LEUVEN K U RES & DEV (BE) | 2015-05-20 | — | — | EP | claimed |
| US-8076310-B2 | Phosphonate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2011-12-13 | — | — | US | claimed |
| EP-2980095-A1 | PHOSPONATE NUCLEOSIDES USEFUL AS ACTIVE INGREDIENTS IN PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS, AND INTERMEDIATES FOR THEIR PRODUCTION | K.U.Leuven Research & Development (BE) | 2016-02-03 | — | — | EP | disclosed |
| US-8076310-B2 | Phosphonate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2011-12-13 | — | — | US | disclosed |