Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 17/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL66593 | 1.00 | CACNA1B (0.85) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL65323 | 1.00 | CACNA1B (0.85) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL2421678 | 1.00 | CACNA1B (0.85) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL16497890 | 0.92 | CACNA1B (1.00) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL67427 | 0.92 | CACNA1B (1.00) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL67089 | 0.92 | CACNA1B (1.00) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL2417881 | 0.92 | CACNA1B (1.00) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL66357 | 0.90 | CACNA1B (0.84) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL2424607 | 0.90 | CACNA1B (0.84) | CACNA1BKCNH2GAAHPGD | |
| SCHEMBL16498680 | 0.89 | CACNA1B (0.81) | CACNA1BKCNH2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011149995-A1 | NOVEL SUBSTITUTED OCTAHYDROCYCLOPENTA [C]PYRROL-4-AMINES AS CALCIUM CHANNEL BLOCKERS | ABBOTT LABORATORIES (US) | 2011-12-01 | — | — | WO | claimed |