Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.44 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.43 |
| ▸ | GCK | P35557 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012447 | 0.87 | MCL1 (0.52) | NR4A2NPC1RAB9ATP53HTT | |
| SCHEMBL16498112 | 0.84 | PARP10 (0.51) | TP53HTTALKBH1MEN1KMT2A | |
| SCHEMBL16498677 | 0.82 | LRRK2 (0.48) | NR4A2MCL1MRGPRX4ALKBH1MEN1 | |
| SCHEMBL16498119 | 0.80 | FFAR1 (0.42) | HTTMRGPRX4SGMS2LRRK2 | |
| SCHEMBL2292252 | 0.79 | TP53 (0.62) | NR4A2NPC1RAB9ATP53HTT | |
| SCHEMBL16498161 | 0.78 | SYK (0.44) | NPC1RAB9AKMT2A | |
| SCHEMBL16498273 | 0.77 | NAPRT (0.39) | LRRK2 | |
| SCHEMBL16498100 | 0.75 | GRM4 (0.52) | SGMS2MEN1KMT2ALRRK2 | |
| SCHEMBL16498135 | 0.75 | GRM4 (0.49) | NR4A2MEN1KMT2ALRRK2 | |
| SCHEMBL16498549 | 0.73 | NAPRT (0.40) | MRGPRX4LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151651-A1 | BENZODIAZEPINE COMPOUNDS USEFUL FOR THE TREATMENT OF HEPATITIS C | ARROW THERAPEUTICS LIMITED (GB) | 2011-12-08 | — | — | WO | disclosed |