Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 4/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9986595 | 1.00 | PDE10A (0.47) | PDE10AKDM4EALDH1A1HPGDAHR | |
| SCHEMBL12071547 | 0.93 | PDE3B (0.48) | PDE10AKDM4EALDH1A1HPGDAHR | |
| SCHEMBL31611876 | 0.92 | TNKS (0.51) | KDM4EALDH1A1HPGDAHRTNKS | |
| SCHEMBL12070664 | 0.83 | NQO2 (0.42) | TNKSTNKS2PDE3BPDE3APARP2 | |
| SCHEMBL14927080 | 0.83 | PARP1 (0.47) | KDM4EALDH1A1HPGDTNKSTNKS2 | |
| SCHEMBL12070655 | 0.79 | KMT2A (0.42) | PDE10AKDM4EALDH1A1HPGDTNKS | |
| SCHEMBL31589365 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1HPGDAHRTNKS | |
| SCHEMBL14927077 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HPGDTNKSTNKS2 | |
| SCHEMBL14927044 | 0.77 | KMT2A (0.40) | TNKSTNKS2PARP2GUSBMEN1 | |
| SCHEMBL874164 | 0.76 | GUSB (0.65) | TNKSTNKS2PARP2GUSBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156626-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2011-12-15 | — | — | WO | disclosed |