Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A2 | O00482 | 1/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | TLR4 | O00206 | 3/20 | 0.32 |
| ▸ | CD14 | P08571 | 3/20 | 0.32 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | RRM1 | P23921 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046764 | 0.86 | CYP1A2 (0.34) | NR5A2NR5A1F10PRSS1SCN2A | |
| SCHEMBL13992488 | 0.86 | CYP1A2 (0.34) | NR5A2NR5A1F10PRSS1SCN2A | |
| SCHEMBL13992491 | 0.81 | TLR4 (0.34) | F10PRSS1TLR4CD14LY96 | |
| SCHEMBL14213237 | 0.79 | TLR4 (0.33) | F10PRSS1TLR4CD14LY96 | |
| SCHEMBL13992486 | 0.79 | TLR4 (0.33) | F10PRSS1TLR4CD14LY96 | |
| SCHEMBL13992487 | 0.75 | CYP1A2 (0.32) | SCN2AHTR1DHTR1BCYP1A2CYP2D6 | |
| SCHEMBL10046751 | 0.75 | HTR1D (0.34) | NR5A2NR5A1F10PRSS1SCN2A | |
| SCHEMBL14680975 | 0.75 | KDM4E (0.43) | F10PRSS1TLR4CD14LY96 | |
| SCHEMBL10046776 | 0.74 | HTR1D (0.33) | F10PRSS1SCN2AHTR1DHTR1B | |
| SCHEMBL10046769 | 0.72 | TLR4 (0.33) | NR5A2NR5A1SCN2ATLR4CD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802291-B1 | CALIXARENE-BASED PEPTIDE CONFORMATION MIMETICS, METHODS OF USE, AND METHODS OF MAKING | UNIV MINNESOTA (US) | 2011-12-07 | — | — | EP | disclosed |