Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 10/20 | 0.67 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650634 | 1.00 | NQO2 (0.67) | NQO2ESR1PTGS2CYP1A1CYP1B1 | |
| SCHEMBL1650904 | 0.92 | NQO2 (0.59) | NQO2ESR1PTGS2CYP1A1CYP1B1 | |
| SCHEMBL1651028 | 0.90 | NQO2 (0.54) | NQO2ESR1PTGS2CYP1A1CYP1B1 | |
| SCHEMBL1651030 | 0.90 | NQO2 (0.54) | NQO2ESR1PTGS2CYP1A1CYP1B1 | |
| SCHEMBL1650706 | 0.88 | NQO2 (0.51) | NQO2CYP1A1CYP1B1ABL1ABCB1 | |
| SCHEMBL1650710 | 0.88 | NQO2 (0.51) | NQO2CYP1A1CYP1B1ABL1ABCB1 | |
| SCHEMBL1652049 | 0.82 | NQO2 (0.49) | NQO2PTGS2CYP1A1CYP1B1ABL1 | |
| SCHEMBL1651473 | 0.81 | PDE4A (0.51) | NQO2ABL1BCRALDH1A1PDE4A | |
| SCHEMBL1651475 | 0.81 | PDE4A (0.51) | NQO2ABL1BCRALDH1A1PDE4A | |
| SCHEMBL1650451 | 0.80 | MEN1 (0.59) | NQO2PTGS2CYP1A1CYP1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530512-B2 | Broad spectrum gram-positive antimicrobials and anthelmintics with efficacy against drug-resistant strains and Mycobacterium species | MONTE AARON P (US) | 2013-09-10 | — | — | US | disclosed |
| US-20110092578-A1 | Broad Spectrum Gram-Positive Antimicrobials and Anthelmintics with Efficacy Against Drug-Resistant Strains and Mycobacterium Species | MONTE AARON P | 2011-04-21 | — | — | US | disclosed |
| US-20070292545-A1 | ANTI-INFECTIVE AGENTS AND METHODS OF USE | WISYS TECHNOLOGY FOUNDATION | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092578-A1 | Broad Spectrum Gram-Positive Antimicrobials and Anthelmintics with Efficacy Against Drug-Resistant Strains and Mycobacterium Species | ABCC1, H1-3, H1-2 | NQO2 91/4885ESR1 1840/4885PTGS2 630/4885 |
| US-20070292545-A1 | ANTI-INFECTIVE AGENTS AND METHODS OF USE | H1-3, H1-0, H1-2 | NQO2 28/4885ESR1 1717/4885PTGS2 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.