SCHEMBL16507835

SCHEMBL16507835

C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](C)CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ NPY5R Q15761 9/20 0.55
▸ NPY4R P50391 9/20 0.55
▸ NPY1R P25929 8/20 0.55
▸ NPY2R P49146 6/20 0.52
▸ OPRM1 P35372 3/20 0.50
▸ OPRK1 P41145 3/20 0.50
▸ FURIN P09958 1/20 0.50
▸ TFPI P10646 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507808 0.96 NPY4R (0.55) NPY5RNPY4RNPY1RNPY2ROPRM1
SCHEMBL16508051 0.92 NPY5R (0.54) NPY5RNPY4RNPY1RNPY2ROPRM1
SCHEMBL16508043 0.91 NPY4R (0.59) NPY5RNPY4RNPY1RNPY2ROPRM1
SCHEMBL16508042 0.89 NPY4R (0.58) NPY5RNPY4RNPY1RNPY2ROPRM1
SCHEMBL16507987 0.88 NPY4R (0.59) NPY5RNPY4RNPY1RNPY2ROPRM1
SCHEMBL22133174 0.88 NPY4R (0.57) NPY5RNPY4RNPY1RNPY2RFURIN
SCHEMBL22133048 0.88 NPY4R (0.58) NPY5RNPY4RNPY1RNPY2R
SCHEMBL13445658 0.87 NPY4R (0.58) NPY5RNPY4RNPY1RNPY2ROPRM1
SCHEMBL29641086 0.87 NPY4R (0.60) NPY5RNPY4RNPY1RNPY2R
SCHEMBL22133047 0.86 NPY4R (0.56) NPY5RNPY4RNPY1RNPY2ROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR NPY5R 1478/4885NPY4R 1387/4885NPY1R 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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