SCHEMBL16507940

SCHEMBL16507940

CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)NC)[C@@H](C)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 2/20 0.46
▸ GCGR P47871 1/20 0.46
▸ GIPR P48546 1/20 0.46
▸ TLR2 O60603 1/20 0.44
▸ ECE1 P42892 1/20 0.42
▸ MUS81 Q96NY9 1/20 0.42
▸ NMT2 O60551 2/20 0.41
▸ NMT1 P30419 2/20 0.41
▸ NPY4R P50391 4/20 0.41
▸ NPY1R P25929 3/20 0.41
▸ NPY5R Q15761 3/20 0.41
▸ NPY2R P49146 1/20 0.41
▸ KISS1R Q969F8 1/20 0.40
▸ RXFP1 Q9HBX9 1/20 0.40
▸ OPRL1 P41146 1/20 0.40
▸ BMP1 P13497 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507975 0.97 NPY4R (0.43) GLP1RGCGRGIPRTLR2ECE1
SCHEMBL16507960 0.94 GLP1R (0.46) GLP1RGCGRGIPRECE1MUS81
SCHEMBL16507786 0.94 GLP1R (0.46) GLP1RGCGRGIPRECE1MUS81
SCHEMBL16507939 0.94 GLP1R (0.46) GLP1RGCGRGIPRECE1MUS81
SCHEMBL16509013 0.93 NPY4R (0.49) GLP1RGCGRGIPRTLR2ECE1
SCHEMBL16508475 0.92 NPY4R (0.47) TLR2NMT2NMT1NPY4RNPY1R
SCHEMBL16508084 0.92 GLP1R (0.46) GLP1RGCGRGIPRTLR2ECE1
SCHEMBL16508481 0.91 TLR2 (0.52) GLP1RGCGRGIPRTLR2NMT2
SCHEMBL13356170 0.91 TLR2 (0.48) GLP1RGCGRGIPRTLR2NMT2
SCHEMBL16507902 0.90 NPY5R (0.43) GLP1RGCGRGIPRTLR2NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR GLP1R 120/4885GCGR 171/4885GIPR 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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