SCHEMBL16507988

SCHEMBL16507988

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](C)[C@@H](C)O)C(N)=O

nearest known ligand 0.70

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 17/20 0.70
▸ NPY1R P25929 10/20 0.70
▸ NPY5R Q15761 9/20 0.70
▸ NPY2R P49146 6/20 0.65
▸ TFPI P10646 1/20 0.58
▸ NPBWR1 P48145 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507977 1.00 NPY4R (0.70) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL16508017 0.99 NPY4R (0.68) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL16507986 0.96 NPY4R (0.75) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16507911 0.96 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16507904 0.96 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16508066 0.92 NPY4R (0.73) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL16508036 0.92 NPY4R (0.70) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL16508125 0.90 NPY4R (0.72) NPY4RNPY1RNPY5RNPY2R
SCHEMBL16507980 0.90 NPY4R (0.53) NPY4RNPY1RNPY5RNPY2RTFPI
SCHEMBL16508144 0.90 NPY4R (0.68) NPY4RNPY1RNPY5RNPY2RTFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR NPY4R 1387/4885NPY1R 800/4885NPY5R 1478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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