SCHEMBL16508136

SCHEMBL16508136

CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NC

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 17/20 0.69
NPY5R Q15761 10/20 0.69
NPY1R P25929 10/20 0.69
NPY2R P49146 7/20 0.69
GRIA1 P42261 1/20 0.56
KISS1R Q969F8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16507970 0.95 NPY4R (0.69) NPY4RNPY5RNPY1RNPY2RGRIA1
SCHEMBL16507757 0.93 NPY4R (0.79) NPY4RNPY5RNPY1RNPY2RKISS1R
SCHEMBL16299120 0.92 NPY4R (0.58) NPY4RNPY5RNPY1RNPY2RKISS1R
SCHEMBL16508138 0.92 NPY4R (0.60) NPY4RNPY5RNPY1RNPY2RKISS1R
SCHEMBL23230088 0.91 NPY4R (0.66) NPY4RNPY5RNPY1RNPY2RGRIA1
SCHEMBL16507879 0.91 NPY4R (0.79) NPY4RNPY5RNPY1RNPY2RKISS1R
SCHEMBL16507934 0.90 NPY4R (0.65) NPY4RNPY5RNPY1RNPY2RGRIA1
SCHEMBL16507963 0.89 NPY4R (0.84) NPY4RNPY5RNPY1RNPY2R
SCHEMBL16507760 0.88 NPY4R (0.72) NPY4RNPY5RNPY1RNPY2RKISS1R
SCHEMBL18237138 0.87 NPY4R (0.62) NPY4RNPY5RNPY1RNPY2RGRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS ANTHOR THERAPEUTICS, INC. 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294738-A1 PTHR1 RECEPTOR COMPOUNDS PTH1R, MC1R, CASR NPY4R 1387/4885NPY5R 1478/4885NPY1R 800/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.