SCHEMBL16508607

SCHEMBL16508607

CNC(=O)NNc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
GAA P10253 2/20 0.32
NOTUM Q6P988 1/20 0.31
F10 P00742 1/20 0.30
HCRTR1 O43613 1/20 0.30
HCRTR2 O43614 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472295 0.91 CA1 (0.35) CA1CA2GAAF10HCRTR1
SCHEMBL566673 0.90 F10 (0.35) CA1CA2GAAF10
SCHEMBL472769 0.89 CA1 (0.34) CA1CA2GAAF10HCRTR1
SCHEMBL472622 0.89 CA1 (0.33) CA1CA2GAAF10HCRTR1
SCHEMBL472683 0.88 CA1 (0.34) CA1CA2GAA
SCHEMBL565285 0.88 CA1 (0.34) CA1CA2GAAF10
SCHEMBL10039190 0.88 KCNJ6 (0.39) CA1CA2GAAF10
SCHEMBL472694 0.86 NPSR1 (0.33) CA1CA2GAA
SCHEMBL10132745 0.86 HTT (0.35) CA1CA2GAAF10
SCHEMBL472765 0.86 GAA (0.35) CA1CA2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294840-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL H1-4, H1-2, H1-0 CA1 1099/4885CA2 670/4885GAA 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.