Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9990091 | 0.83 | DPP4 (0.54) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL9990097 | 0.83 | DPP4 (0.54) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL18104703 | 0.64 | DPP4 (1.00) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL13472178 | 0.62 | DPP4 (0.51) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL16102356 | 0.62 | KMT2A (0.55) | DPP4DPP8 | |
| SCHEMBL16993659 | 0.61 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL30272063 | 0.61 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL16993660 | 0.61 | DPP4 (0.59) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL9991047 | 0.61 | DPP4 (0.73) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL14960664 | 0.61 | DPP4 (0.73) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151443-A1 | A NOVEL SYNTHETIC APPROACH TO ß-AMINOBUTYRYL SUBSTITUTED COMPOUNDS | LEK PHARMACEUTICALS D.D. (SI) | 2011-12-08 | — | — | WO | disclosed |