Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16511695 | 0.99 | MAPT (0.38) | MAPTKMT2AMEN1L3MBTL1ELANE | |
| SCHEMBL16511897 | 0.86 | POLB (0.38) | MAPTKMT2AMEN1POLB | |
| SCHEMBL16511711 | 0.85 | POLB (0.39) | MAPTPOLB | |
| SCHEMBL16511968 | 0.82 | MAPT (0.35) | MAPTL3MBTL1POLB | |
| SCHEMBL16511697 | 0.81 | MAPT (0.37) | MAPTPOLB | |
| SCHEMBL16511969 | 0.81 | MAPT (0.35) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL16511967 | 0.81 | MAPT (0.35) | MAPTKMT2AMEN1POLB | |
| SCHEMBL16511693 | 0.81 | MAPT (0.37) | MAPTPOLB | |
| SCHEMBL16511694 | 0.81 | MAPT (0.37) | MAPTKMT2AMEN1POLB | |
| SCHEMBL16511891 | 0.81 | MAPT (0.34) | MAPTKMT2AMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011153865-A1 | 3-ORTHO-METHYLPHENYL-2-OXO-1-OXASPIRO[4,4]NON-3-EN-4-OL WITH BIOLOGICAL ACTIVITY, DERIVATIVES AND PREPARATION METHOD THEREOF | 湖南化工研究院 (CN) | 2011-12-15 | — | — | WO | disclosed |