SCHEMBL1651720

SCHEMBL1651720

CCC(c1ccccc1)c1c(O)oc2ccccc2c1=O

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 13/20 0.68
NQO1 P15559 2/20 0.51
VKORC1 Q9BQB6 3/20 0.50
HSD17B10 Q99714 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
ALB P02768 1/20 0.50
PCSK7 Q16549 1/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP3A4 P08684 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL414250 1.00 CYP2C9 (0.68) CYP2C9NQO1VKORC1HSD17B10KDM4E
SCHEMBL1479347 0.85 CYP2C9 (0.73) CYP2C9VKORC1HSD17B10KDM4EALDH1A1
SCHEMBL20806 0.85 CYP2C9 (0.73) CYP2C9VKORC1HSD17B10KDM4EALDH1A1
SCHEMBL136434 0.85 CYP2C9 (0.73) CYP2C9VKORC1HSD17B10KDM4EALDH1A1
Phenprocoumon SCHEMBL24500472 0.81 CYP2C9 (1.00) CYP2C9NQO1VKORC1HSD17B10KDM4E
Phenprocoumon SCHEMBL29392123 0.81 CYP2C9 (1.00) CYP2C9NQO1VKORC1HSD17B10KDM4E
Phenprocoumon SCHEMBL24500477 0.81 CYP2C9 (1.00) CYP2C9NQO1VKORC1HSD17B10KDM4E
Phenprocoumon SCHEMBL43031 0.81 CYP2C9 (1.00) CYP2C9NQO1VKORC1HSD17B10KDM4E
SCHEMBL1649847 0.80 CYP2C9 (0.50) CYP2C9NQO1HSD17B10KDM4EALDH1A1
Phosphoric Acid SCHEMBL28278851 0.80 CYP2C9 (0.66) CYP2C9VKORC1HSD17B10KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-7927613-B2 Pharmaceutical co-crystal compositions UNIVERSITY OF SOUTH FLORIDA (US) 2011-04-19 US disclosed
US-7790905-B2 Pharmaceutical propylene glycol solvate compositions MCNEIL-PPC, INC. (US) 2010-09-07 US disclosed