Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.57 |
| ▸ | PKD1 | P98161 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16505281 | 0.93 | MAP3K14 (0.67) | MAP3K14 | |
| SCHEMBL16505430 | 0.89 | MAP3K14 (0.54) | MAP3K14PKD1 | |
| SCHEMBL16517259 | 0.88 | MAP3K14 (0.58) | MAP3K14 | |
| SCHEMBL16505722 | 0.83 | MAP3K14 (0.62) | MAP3K14 | |
| SCHEMBL16505718 | 0.82 | MAP3K14 (0.68) | MAP3K14 | |
| SCHEMBL16505615 | 0.82 | MAP3K14 (0.75) | MAP3K14 | |
| SCHEMBL16505023 | 0.82 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL16505788 | 0.82 | MAP3K14 (0.62) | MAP3K14PKD1 | |
| SCHEMBL16517763 | 0.82 | MAP3K14 (0.62) | MAP3K14PKD1 | |
| SCHEMBL16506417 | 0.81 | MAP3K14 (0.67) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036229-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. Hoffmann-La Roche AG (CH) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015025026-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2015-02-26 | — | — | WO | disclosed |