Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16517517 | 0.92 | MAP3K14 (0.39) | MAP3K14 | |
| SCHEMBL16517568 | 0.84 | CYP1A2 (0.41) | MAP3K14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16517261 | 0.79 | MAP3K14 (0.38) | MAP3K14 | |
| SCHEMBL16517764 | 0.79 | CYP1A2 (0.40) | MAP3K14MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL16533810 | 0.79 | MAP3K14 (0.46) | MAP3K14 | |
| SCHEMBL16517654 | 0.79 | MAP3K14 (0.40) | MAP3K14PIN1 | |
| SCHEMBL16533787 | 0.78 | MAP3K14 (0.46) | MAP3K14 | |
| SCHEMBL16517369 | 0.77 | MAP3K14 (0.53) | MAP3K14ALDH1A1MEN1KMT2A | |
| SCHEMBL16517790 | 0.76 | MAP3K14 (0.46) | MAP3K14 | |
| SCHEMBL16517538 | 0.76 | MAP3K14 (0.47) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036229-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. Hoffmann-La Roche AG (CH) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015025026-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2015-02-26 | — | — | WO | disclosed |