Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 1/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16517391 | 0.90 | ELANE (0.47) | RPA1NPBWR1ELANEMAP3K14MEN1 | |
| SCHEMBL16516399 | 0.90 | RPA1 (0.46) | RPA1NPBWR1ELANEMAP3K14EGFR | |
| SCHEMBL16516797 | 0.79 | PDE4A (0.44) | RPA1KDM4ECHEK1AURKACSNK1A1 | |
| SCHEMBL16516512 | 0.78 | RPA1 (0.47) | RPA1NPBWR1ELANEMAP3K14CHEK1 | |
| SCHEMBL16516955 | 0.77 | ELANE (0.41) | RPA1NPBWR1ELANEKDM4EMEN1 | |
| SCHEMBL16516406 | 0.77 | ELANE (0.41) | RPA1NPBWR1ELANEL3MBTL1MEN1 | |
| SCHEMBL16517380 | 0.76 | RPA1 (0.40) | RPA1MAP3K14CHEK1AURKACSNK1A1 | |
| SCHEMBL16516840 | 0.75 | RPA1 (0.56) | RPA1NPBWR1ELANEKDM4ETHRB | |
| SCHEMBL16532418 | 0.75 | MAP3K14 (0.57) | RPA1NPBWR1MAP3K14EGFRERBB2 | |
| SCHEMBL16532324 | 0.75 | ELANE (0.49) | RPA1NPBWR1ELANETHRBMAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036230-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. Hoffmann-La Roche AG (CH) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015025025-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2015-02-26 | — | — | WO | disclosed |