Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12175497 | 0.85 | PRCP (0.79) | PRCP | |
| SCHEMBL14650737 | 0.80 | PRCP (0.77) | PRCP | |
| SCHEMBL14650814 | 0.77 | PRCP (1.00) | PRCP | |
| SCHEMBL12175461 | 0.70 | PRCP (0.57) | PRCP | |
| SCHEMBL12175456 | 0.68 | PRCP (1.00) | PRCP | |
| SCHEMBL14650735 | 0.68 | PRCP (0.84) | PRCP | |
| SCHEMBL12175458 | 0.67 | PRCP (1.00) | PRCP | |
| SCHEMBL14650738 | 0.66 | PRCP (0.87) | PRCP | |
| SCHEMBL12175494 | 0.66 | PRCP (1.00) | PRCP | |
| SCHEMBL14650774 | 0.65 | PRCP (0.83) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563764-B1 | NOVEL SPIROPIPERIDINE PROLYLCARBOXYPEPTIDASE INHIBITORS | MERCK SHARP & DOHME (US) | 2015-02-25 | — | — | EP | disclosed |