SCHEMBL16522985

SCHEMBL16522985

CC1(C)c2ccccc2-c2ccc(-c3nc(-c4ccccc4)nc(-n4c5ccccc5c5cc6c7ccccc7n(-c7ccccc7)c6cc54)n3)cc21

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.36
▸ ATM Q13315 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36
▸ PTGER4 P35408 1/20 0.32
▸ RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16521257 0.98 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL24216365 0.97 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL30021136 0.97 KDM4E (0.37) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL16522988 0.97 KDM4E (0.37) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL16521256 0.95 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL24216736 0.94 KDM4E (0.35) KDM4EATML3MBTL1PTGER4
SCHEMBL19474329 0.93 KDM4E (0.31) KDM4EATML3MBTL1
SCHEMBL23318116 0.93 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL23318244 0.92 KDM4E (0.36) KDM4EATML3MBTL1PTGER4RXFP1
SCHEMBL15248434 0.92 KDM4E (0.38) KDM4EATML3MBTL1PTGER4RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3425693-B1 METHOD FOR PRODUCING AN ORGANIC LIGHT-EMITTING DIODE UNIVERSAL DISPLAY CORP (US) 2023-04-26 — — EP disclosed
US-20200335702-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-10-22 — — US disclosed
US-10749114-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 — — US disclosed
EP-3425693-A2 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICES Universal Display Corporation (US) 2019-01-09 — — EP disclosed
EP-2849240-A2 Organic electroluminescent materials and devices cross-reference to related applications Universal Display Corporation (US) 2015-03-18 — — EP disclosed
US-20150053939-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-02-26 — — US disclosed
US-20150053939-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-02-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10749114-B2 Organic electroluminescent materials and devices OCIAD2, JUND, OCIAD1 KDM4E 1729/4885ATM 3629/4885L3MBTL1 980/4885
US-20200335702-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, JUND, OCIAD1 KDM4E 1729/4885ATM 3629/4885L3MBTL1 980/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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