Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.65 |
| ▸ | PKD1 | P98161 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16505655 | 1.00 | MAP3K14 (0.65) | MAP3K14PKD1 | |
| SCHEMBL16516869 | 1.00 | MAP3K14 (0.65) | MAP3K14PKD1 | |
| SCHEMBL16505796 | 0.92 | MAP3K14 (0.71) | MAP3K14PKD1 | |
| SCHEMBL16505370 | 0.85 | MAP3K14 (0.75) | MAP3K14PKD1 | |
| SCHEMBL16505432 | 0.84 | MAP3K14 (0.56) | MAP3K14 | |
| SCHEMBL16505433 | 0.84 | MAP3K14 (0.56) | MAP3K14 | |
| SCHEMBL16505904 | 0.84 | MAP3K14 (0.56) | MAP3K14 | |
| SCHEMBL16505010 | 0.81 | MAP3K14 (0.79) | MAP3K14PKD1 | |
| SCHEMBL16505007 | 0.81 | MAP3K14 (0.79) | MAP3K14PKD1 | |
| SCHEMBL16505948 | 0.81 | MAP3K14 (0.79) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015025026-A1 | ALKYNYL ALCOHOLS AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2015-02-26 | — | — | WO | disclosed |