Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 20/20 | 0.80 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541163 | 0.87 | CAPN1 (0.82) | CAPN1 | |
| SCHEMBL15324925 | 0.86 | CAPN1 (0.59) | CAPN1 | |
| SCHEMBL15320164 | 0.85 | CAPN1 (0.79) | CAPN1 | |
| SCHEMBL15319156 | 0.84 | CAPN1 (0.78) | CAPN1 | |
| SCHEMBL16535212 | 0.84 | CAPN1 (0.78) | CAPN1 | |
| SCHEMBL16534682 | 0.84 | CAPN1 (0.78) | CAPN1CTSS | |
| SCHEMBL15323538 | 0.84 | CAPN1 (0.78) | CAPN1 | |
| SCHEMBL16535076 | 0.84 | CAPN1 (0.78) | CAPN1CTSS | |
| SCHEMBL541303 | 0.84 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL541212 | 0.84 | CAPN1 (1.00) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150545-B2 | Carboxamide compounds and their use as calpain inhibitors V | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-10-06 | — | — | US | claimed |
| US-20150065477-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-03-05 | — | — | US | claimed |
| US-9150545-B2 | Carboxamide compounds and their use as calpain inhibitors V | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-10-06 | — | — | US | disclosed |
| US-20150065477-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V | AbbVie Deutschland GmbH & Co. KG (DE) | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150065477-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS V | CAPN1, CAPN2, CAPNS1 | CAPN1 1/4885CTSS 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.