SCHEMBL16536723

SCHEMBL16536723

C=CC(=O)OCCCC[SiH2]CC(OC)OC

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.55
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
HPGD P15428 1/20 0.50
TP53 P04637 3/20 0.42
HIF1A Q16665 3/20 0.42
HSD17B10 Q99714 1/20 0.42
THRB P10828 2/20 0.36
ATM Q13315 1/20 0.33
HCAR2 Q8TDS4 3/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537902 0.98 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16536942 0.95 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537824 0.89 TSHR (0.46) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537205 0.88 TSHR (0.51) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537981 0.87 TSHR (0.54) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16536773 0.85 TSHR (0.51) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537725 0.84 TSHR (0.54) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537056 0.83 TSHR (0.49) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL10797805 0.80 TSHR (0.53) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL29035593 0.79 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed