SCHEMBL16536770

SCHEMBL16536770

C=CC(=O)OC(CCC)[Si](CC)(OCC)OCC

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
HPGD P15428 1/20 0.35
THRB P10828 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537721 0.91 TSHR (0.43) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL16537310 0.89 TSHR (0.35) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL1067079 0.87 TSHR (0.34) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL16536721 0.86 TSHR (0.36) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL16537457 0.84 TSHR (0.36) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL16536927 0.84 TSHR (0.36) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL1680181 0.84 TSHR (0.37) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL16536922 0.83 TSHR (0.36) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL16537090 0.83 TSHR (0.36) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL16537908 0.81 TSHR (0.33) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed