SCHEMBL16537366

SCHEMBL16537366

C=Cc1cccc(CO[Si](C)(C)OCC)c1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
PTPN1 P18031 1/20 0.32
FAAH O00519 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
IDO1 P14902 1/20 0.30
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537466 0.88 TP53 (0.40) TP53TDP1MAOAMAOBPTPN1
SCHEMBL16537338 0.86 TDP1 (0.41) TP53TDP1MAOAMAOBFAAH
SCHEMBL16537905 0.86 TP53 (0.41) TP53TDP1MAOAMAOBPTPN1
SCHEMBL16537429 0.85 TP53 (0.38) TP53TDP1MAOAMAOBPTPN1
SCHEMBL16537532 0.85 TP53 (0.38) TP53TDP1FAAH
SCHEMBL16536777 0.84 TP53 (0.39) TP53TDP1MAOAMAOBPTPN1
SCHEMBL16537995 0.84 TP53 (0.39) TP53TDP1MAOAMAOBPTPN1
SCHEMBL16536307 0.83 TP53 (0.36) TP53TDP1
SCHEMBL16537397 0.83 TP53 (0.36) TP53TDP1
SCHEMBL16536784 0.81 TP53 (0.37) TP53TDP1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed