SCHEMBL16539

SCHEMBL16539

[CH]1C=COS1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL431361 0.86
SCHEMBL8841950 0.67
SCHEMBL8112356 0.67
SCHEMBL62472 0.67
SCHEMBL30706490 0.65
Lithium SCHEMBL30706491 0.65
SCHEMBL118287 0.56
SCHEMBL2138977 0.52
SCHEMBL1518002 0.39
Water SCHEMBL19761 0.39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2961 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024108147-A1 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2024-05-23 WO claimed
US-20210238210-A1 ANTIVIRAL COMPOUNDS VIROVAX LLC 2021-08-05 US claimed
EP-3484892-B1 1,2,4-TRIAZOLO-[3,4-B]-1,3,4-THIADIAZOLE DERIVATIVES GALENICA S A (GR) 2020-08-26 EP claimed
EP-2800738-B1 HETEROCYCLIC COMPOUNDS AND METHODS FOR THEIR USE NOVARTIS AG (CH) 2020-04-08 EP claimed
EP-2047305-B1 ORIENTED POLYMERIC SHEETS EXHIBITING DICHROISM AND ARTICLES CONTAINING THE SAME TRANSITIONS OPTICAL INC (US) 2019-11-20 EP claimed
US-10370388-B2 Heterocyclic compounds and methods of their use NOVARTIS AG (CH) 2019-08-06 US claimed
US-20190194228-A1 NEW 1,2,4-TRIAZOLO-[3,4-b]-1,3,4-THIADIAZOLE DERIVATIVES ENERGONBIO TECHNOLOGIES S.A. (GR) 2019-06-27 US claimed
EP-3484892-A1 NEW 1,2,4-TRIAZOLO-[3,4-b]-1,3,4-THIADIAZOLE DERIVATIVES Galenica S.A. (GR) 2019-05-22 EP claimed
US-10205108-B2 Compound CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-02-12 US claimed
US-RE47009-E1 HDAC inhibitors and therapeutic methods using the same THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2018-08-28 US claimed
WO-2002092588-A2 AROMATIC SULFONE HYDROXAMATES AND THEIR USE AS PROTEASE INHIBITORS PHARMACIA CORPORATION (US) 2002-11-21 WO claimed
US-6478988-B1 Photochromic substituted naphthopyran compounds BMC VISION-EASE LENS, INC. 2002-11-12 US claimed
EP-1065206-B1 Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents PFIZER (US) 2002-10-09 EP claimed
US-20020132223-A1 Methods for modulating activity of the FXR nuclear receptor CITY OF HOPE (US) 2002-09-19 US claimed
US-20020080451-A1 Novel naphthopyran compounds, photoresponsive compositions and lenses VISION-EASE LENS, INC. 2002-06-27 US claimed
WO-2002038563-A2 CONDENSED PYRAZINDIONE DERIVATIVES AS PDE INHIBITORS LILLY ICOS LLC (US) 2002-05-16 WO claimed
EP-1065206-A1 Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents PFIZER INC. (US) 2001-01-03 EP claimed
US-6127372-A FOR TREATMENT OR PREVENTION OF VIRAL DISEASES, ESPECIALLY AIDS OR HIV VERTEX PHARMACEUTICALS, INCORPORATED (US) 2000-10-03 US claimed
EP-1016702-A2 Photochromic substituted naphthopyran compounds BMC Vision-Ease Lens Inc. (US) 2000-07-05 EP claimed
US-5637590-A Rapamycin amidino carbamates AMERICAN HOME PRODUCTS CORPORATION (US) 1997-06-10 US claimed