SCHEMBL16539155

SCHEMBL16539155

CC(C)(C)OC(=O)CCCCCCCCCCCCCCC(=O)NC(CCC(=O)NCCCCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 5/20 0.52
▸ KMT2A Q03164 1/20 0.48
▸ MDM2 Q00987 6/20 0.47
▸ TLR1 Q15399 1/20 0.45
▸ MDM4 O15151 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ SIRT2 Q8IXJ6 2/20 0.41
▸ SIRT1 Q96EB6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17746964 1.00 TLR2 (0.52) TLR2KMT2AMDM2TLR1MDM4
SCHEMBL17746966 1.00 TLR2 (0.52) TLR2KMT2AMDM2TLR1MDM4
SCHEMBL31631398 0.96 TLR2 (0.49) TLR2KMT2AMDM2TLR1SIRT2
SCHEMBL31624365 0.96 TLR2 (0.49) TLR2KMT2AMDM2TLR1SIRT2
SCHEMBL31631367 0.96 TLR2 (0.49) TLR2KMT2AMDM2TLR1SIRT2
SCHEMBL17747059 0.95 TLR2 (0.54) TLR2KMT2AMDM2MDM4TP53
SCHEMBL17747057 0.95 TLR2 (0.54) TLR2KMT2AMDM2MDM4TP53
SCHEMBL29232445 0.94 TLR2 (0.51) TLR2KMT2AMDM2TLR1MDM4
SCHEMBL29232441 0.94 TLR2 (0.51) TLR2KMT2AMDM2TLR1MDM4
SCHEMBL15387383 0.94 TLR2 (0.60) TLR2KMT2AMDM2TLR1SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441760-B2 Amino diacids containing peptide modifiers CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-10-14 — — US disclosed
US-20240002433-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2024-01-04 — — US disclosed
US-11634455-B2 Amino diacids containing peptide modifiers CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2023-04-25 — — US disclosed
US-11634455-B2 Amino diacids containing peptide modifiers CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2023-04-25 — — US disclosed
EP-3038658-B1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S A (GR) 2020-11-04 — — EP disclosed
EP-3038658-B1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S A (GR) 2020-11-04 — — EP disclosed
EP-3725801-A2 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS Chemical & Biopharmaceutical Laboratories of Patras S.A. (GR) 2020-10-21 — — EP disclosed
EP-3725801-A2 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS Chemical & Biopharmaceutical Laboratories of Patras S.A. (GR) 2020-10-21 — — EP disclosed
US-20190177362-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2019-06-13 — — US disclosed
US-20190177362-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2019-06-13 — — US disclosed
US-20160207957-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2016-07-21 — — US disclosed
US-20160207957-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2016-07-21 — — US disclosed
EP-3038658-A2 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS Chemical & Biopharmaceutical Laboratories of Patras S.A. (GR) 2016-07-06 — — EP disclosed
WO-2015028966-A2 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2015-03-05 — — WO disclosed
WO-2015028966-A2 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2015-03-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441760-B2 Amino diacids containing peptide modifiers PTMS, PEPD, NGLY1 TLR2 4460/4885KMT2A 2057/4885MDM2 1037/4885
US-20160207957-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS PTMS, PEPD, VIP TLR2 4437/4885KMT2A 2174/4885MDM2 1136/4885
US-20190177362-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS PTMS, PEPD, VIP TLR2 4437/4885KMT2A 2174/4885MDM2 1136/4885
US-11634455-B2 Amino diacids containing peptide modifiers PTMS, PEPD, VIP TLR2 4437/4885KMT2A 2174/4885MDM2 1136/4885
US-20240002433-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS PTMS, PEPD, NGLY1 TLR2 4460/4885KMT2A 2057/4885MDM2 1037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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