Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Triacetin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGD | P52209 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triacetin SCHEMBL28247836 | 1.00 | TDP1 (0.52) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL28353528 | 1.00 | TDP1 (0.52) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL4367394 | 0.98 | TDP1 (0.54) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL16468564 | 0.95 | TDP1 (0.52) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL821340 | 0.95 | TDP1 (0.56) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL3870 | 0.95 | TDP1 (0.56) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL16445622 | 0.93 | TDP1 (0.54) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL16446056 | 0.93 | TDP1 (0.54) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL31301065 | 0.93 | TDP1 (0.54) | TDP1ARPRKCAGAALMNA | |
| Triacetin SCHEMBL8012678 | 0.93 | TDP1 (0.54) | TDP1ARPRKCAGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117122089-A | Filter stick, manufacturing method thereof, preparation system and heating cigarette using filter stick | 四川三联新材料有限公司 | 2023-11-28 | — | — | CN | claimed |
| CN-114397269-B | Method for measuring content of triacetin in cigarette filter stick | 湖北中烟工业有限责任公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117122089-A | Filter stick, manufacturing method thereof, preparation system and heating cigarette using filter stick | 四川三联新材料有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-108368306-A | Include the new plastification composite of cellulose acetate | 罗地亚阿塞托有限公司 | 2018-08-03 | — | — | CN | disclosed |
| US-20170319662-A1 | STABLE NON-AQUEOUS SINGLE PHASE VISCOUS VEHICLES AND FORMULATIONS UTILIZING SUCH VEHICLES | ALZA CORPORATION | 2017-11-09 | — | — | US | disclosed |
| US-20170119855-A1 | STABLE NON-AQUEOUS SINGLE PHASE VISCOUS VEHICLES AND FORMULATIONS UTILIZING SUCH VEHICLES | ALZA CORPORATION | 2017-05-04 | — | — | US | disclosed |
| US-20150231256-A1 | STABLE NON-AQUEOUS SINGLE PHASE VISCOUS VEHICLES AND FORMULATIONS UTILIZING SUCH VEHICLES | ALZA CORPORATION | 2015-08-20 | — | — | US | disclosed |
| US-8992961-B2 | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles | INTARCIA THERAPEUTICS, INC. (US) | 2015-03-31 | — | — | US | disclosed |
| EP-1666026-B2 | Non-aqueous single phase biocompatible viscous vehicles and methods for preparing the same | INTARCIA THERAPEUTICS INC (US) | 2015-02-25 | — | — | EP | disclosed |
| US-20140088013-A1 | Complexation of Metal Ions with Polypeptides | DURECT CORP (US) | 2014-03-27 | — | — | US | disclosed |
| EP-0944375-A1 | UNITARY ABSORBENT LAYER | WEYERHAEUSER COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| EP-0943025-A1 | AIR-LAID UNITARY ABSORBENT LAYER | WEYERHAEUSER COMPANY (US) | 1999-09-22 | — | — | EP | disclosed |
| EP-0941157-A1 | UNITARY STRATIFIED COMPOSITE | WEYERHAEUSER COMPANY (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5837627-A | SOLUBILIZED BINDER, ABSORBENT PRODUCTS | WEYERHAEUSER COMPANY (US) | 1998-11-17 | — | — | US | disclosed |
| WO-1998024621-A1 | UNITARY STRATIFIED COMPOSITE | WEYERHAEUSER COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |
| WO-1998024960-A1 | AIR-LAID UNITARY ABSORBENT LAYER | WEYERHAEUSER COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |
| WO-1998024392-A1 | UNITARY ABSORBENT LAYER | WEYERHAEUSER COMPANY (US) | 1998-06-11 | — | — | WO | disclosed |
| EP-0813626-A1 | FIBROUS WEB HAVING IMPROVED STRENGTH AND METHOD OF MAKING THE SAME | WEYERHAEUSER COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5656793-A | HYDRAZODICARBONAMIDE AS REDUCING AGENT, OXOACID SALT AS OXIDIZING AGENT AND COMBUSTION CONTROLLER WITH CATALYTIC FUNCTION OF METAL OXIDE CONTAINING BORON, ALUMINUM AND/OR ZIRCONIUM | EIWA CHEMICAL IND. CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| WO-1996027703-A1 | FIBROUS WEB HAVING IMPROVED STRENGTH AND METHOD OF MAKING THE SAME | WEYERHAEUSER COMPANY (US) | 1996-09-12 | — | — | WO | disclosed |