Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.75 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.75 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.75 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.75 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.75 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.75 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.75 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.75 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16361266 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL19697632 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL1071844 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL24408031 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL18827758 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL24999988 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL16361423 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL24001462 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL1931918 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 | |
| SCHEMBL8659794 | 1.00 | GPBAR1 (0.75) | GPBAR1NR1H4MEN1KMT2AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250258146-A1 | QUANTITATIVE DETECTION METHOD OF MULTIPLE METABOLITES IN BIOLOGICAL SAMPLE AND METABOLIC CHIP | HUMAN METABOLOMICS INSTITUTE INC. (CN) | 2025-08-14 | — | — | US | disclosed |
| US-20140234398-A1 | Dissolution of Arterial Plaque | ATHERONOVA OPERATIONS, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140148422-A1 | TREATMENT OF GLUCOSE INTOLERANCE | ATHERONOVA OPERATIONS, INC. (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140142071-A1 | REGRESSION OF ARTERIAL PLAQUE | ATHERONOVA OPERATIONS, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8697633-B2 | Dissolution of arterial plaque | ATHERONOVA OPERATIONS, INC. (US) | 2014-04-15 | — | — | US | disclosed |
| US-20130029946-A1 | DISSOLUTION OF ARTERIAL PLAQUE | ATHERANOVA OPERATIONS, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-8304383-B2 | Atherosclerosis therapy ; circulation of emulsifiers; using bile salts, saponins or detergent surfactant; concurrent administering with statin | ATHERONOVA OPERATIONS, INC. (US) | 2012-11-06 | — | — | US | disclosed |
| EP-2485738-A2 | COMPOSITIONS AND METHODS FOR TREATING OBESITY | Atheronova Operations, Inc. (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011044523-A2 | COMPOSITIONS AND METHODS FOR TREATING OBESITY | ATHERONOVA OPERATIONS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| US-20110086829-A1 | COMPOSITIONS AND METHODS FOR TREATING OBESITY | ATHERONOVA OPERATIONS, INC. | 2011-04-14 | — | — | US | disclosed |
| WO-2010033637-A1 | DISSOLUTION OF ARTERIAL PLAQUE | Z & Z MEDICAL HOLDINGS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| US-20090035348-A1 | DISSOLUTION OF ARTERIAL PLAQUE | Z & Z MEDICAL HOLDINGS, INC. (US) | 2009-02-05 | — | — | US | disclosed |
| WO-2008144458-A1 | DISSOLUTION OF ARTERIAL CHOLESTEROL PLAQUES BY PHARMACOLOGICALLY INDUCED ELEVATION OF ENDOGENOUS BILE SALTS | Z & Z MEDICAL HOLDINGS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
| US-20080287429-A1 | Dissolution of Arterial Cholesterol Plaques by Pharmacologically Induced Elevation of Endogenous Bile Salts | Z & Z MEDICAL HOLDINGS, INC. (US) | 2008-11-20 | — | — | US | disclosed |
| US-20080187569-A1 | DISSOLUTION OF ARTERIAL PLAQUE | Z & Z MEDICAL HOLDINGS, INC. (US) | 2008-08-07 | — | — | US | disclosed |
| US-20070129425-A1 | Dissolution of arterial cholesterol plaques by pharmacological preparation | Z & Z MEDICAL HOLDINGS, INC. | 2007-06-07 | — | — | US | disclosed |
| WO-2007061820-A2 | DISSOLUTION OF ARTERIAL CHOLESTEROL PLAQUES BY A CLASS OF PHARMACOLOGICAL COMPOUNDS | ZADINI FILIBERTO (US) | 2007-05-31 | — | — | WO | disclosed |
| US-20070116754-A1 | Dissolution of arterial cholesterol plaques by pharmacological preparation | Z & Z MEDICAL HOLDINGS, INC. | 2007-05-24 | — | — | US | disclosed |
| US-20070116755-A1 | Dissolution of arterial cholesterol plaques by pharmacological preparation | Z & Z MEDICAL HOLDINGS, INC. | 2007-05-24 | — | — | US | disclosed |
| US-20070071706-A1 | Lipodissolving dermatological topical preparation | ATHERONOVA OPERATIONS, INC. | 2007-03-29 | — | — | US | disclosed |