Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.45 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16546937 | 0.91 | ESR1 (0.43) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL15930493 | 0.86 | ESR1 (0.49) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL17445471 | 0.85 | ESR1 (0.56) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL17451713 | 0.85 | ESR1 (0.58) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL16546935 | 0.85 | KDM4E (0.46) | ALDH1A1CYP2C19TSHRKDM4E | |
| SCHEMBL14884153 | 0.84 | ESR1 (0.47) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14884122 | 0.83 | ESR1 (0.51) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14884205 | 0.83 | ESR1 (0.46) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14884207 | 0.82 | ESR1 (0.50) | ESR1ESR2GRIA1CACNG8CACNG2 | |
| SCHEMBL14478615 | 0.82 | ESR1 (0.44) | ESR1ESR2GRIA1CACNG8CACNG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9768393-B2 | Condensed-cyclic compound and organic light-emitting device including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-09-19 | — | — | US | disclosed |
| US-9768393-B2 | Condensed-cyclic compound and organic light-emitting device including the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-09-19 | — | — | US | disclosed |
| US-20150060791-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-03-05 | — | — | US | disclosed |
| US-20150060791-A1 | CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-03-05 | — | — | US | disclosed |