⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17585904 | 1.00 | — | — | |
| SCHEMBL21983782 | 0.80 | — | — | |
| SCHEMBL10499893 | 0.79 | — | — | |
| SCHEMBL10499910 | 0.79 | — | — | |
| SCHEMBL6369258 | 0.70 | — | — | |
| SCHEMBL6369262 | 0.70 | — | — | |
| SCHEMBL10290605 | 0.67 | — | — | |
| SCHEMBL17674104 | 0.65 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL17674106 | 0.65 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL24766912 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015031613-A1 | BIARYL ACETAMIDE COMPOUNDS AND METHODS OF USE THEREOF | AMBIT BIOSCIENCES CORPORATION (US) | 2015-03-05 | — | — | WO | disclosed |