Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU3 | Q9UQ49 | 7/20 | 0.71 |
| ▸ | NEU1 | Q99519 | 19/20 | 0.57 |
| ▸ | NEU4 | Q8WWR8 | 2/20 | 0.57 |
| ▸ | NEU2 | Q9Y3R4 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16548126 | 0.90 | NEU3 (0.59) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL16548129 | 0.89 | NEU1 (0.57) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL16548135 | 0.88 | NEU1 (0.73) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL16544472 | 0.87 | NEU3 (0.72) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL26354938 | 0.87 | NEU3 (0.72) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL16548231 | 0.85 | NEU1 (0.56) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL14933700 | 0.83 | NEU3 (1.00) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL22276975 | 0.83 | NEU3 (1.00) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL21164804 | 0.83 | NEU3 (1.00) | NEU3NEU1NEU4NEU2 | |
| SCHEMBL22111639 | 0.80 | NEU2 (0.63) | NEU3NEU1NEU4NEU2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150064282-A1 | USE OF NEU1 SIALIDASE INHIBITORS IN THE TREATMENT OF CANCER | SZEWCZUK, MYRON R. (CA) | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150064282-A1 | USE OF NEU1 SIALIDASE INHIBITORS IN THE TREATMENT OF CANCER | NEU1, NEU2, NEU3 | NEU3 3/4885NEU1 1/4885NEU4 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.