Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 20/20 | 0.80 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL541237 | 0.99 | CAPN1 (0.79) | CAPN1CTSS | |
| SCHEMBL540966 | 0.89 | CAPN1 (1.00) | CAPN1CTSS | |
| SCHEMBL540969 | 0.87 | CAPN1 (0.87) | CAPN1CTSS | |
| SCHEMBL541139 | 0.87 | CAPN1 (0.82) | CAPN1CTSS | |
| SCHEMBL2718056 | 0.86 | CAPN1 (0.80) | CAPN1CTSS | |
| Hydrochloric Acid SCHEMBL540747 | 0.86 | CAPN1 (0.79) | CAPN1CTSS | |
| SCHEMBL541344 | 0.84 | CAPN1 (0.87) | CAPN1CTSS | |
| SCHEMBL541511 | 0.83 | CAPN1 (0.84) | CAPN1CTSS | |
| SCHEMBL2715422 | 0.82 | CAPN1 (0.54) | CAPN1CTSS | |
| SCHEMBL16551503 | 0.82 | CAPN1 (0.83) | CAPN1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2439205-B1 | Carboxamide compounds and their use as calpain inhibitors | ABBVIE DEUTSCHLAND (DE) | 2015-03-11 | — | — | EP | claimed |